Article
Genotypic interactions of renin-angiotensin system genes in myocardial infarction.
International journal of cardiology - 3 Aug 2005
Araújo Messias Antônio, Goulart Luiz Ricardo, Cordeiro Elisângela Rosa, Gatti Renata Ríspoli, Menezes Bruno Soares, Lourenço Clauber, Silva Heyder Diniz
Abstract excerpt
BACKGROUND: Three-gene interactions among the genetic polymorphisms of the renin-angiotensin system (RAS) associated with acute myocardial infarction (AMI) have not been examined in a single population. We hypothesized that all types of gene-to-gene associations may occur in AMI, but that some will have a higher risk, depending on the gene frequencies. METHODS: Polymorphisms of the AGT (M235T), ACE (I/D) and...
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