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Article

Resistance to Arsenic Therapy in Acute Promyelocytic Leukemia

7 May 2014

Abstract excerpt

Although resistance to arsenic trioxide in patients with acute promyelocytic leukemia is very rare, mutations in PML at the site of arsenic binding appears to be the main mechanism of resistance.

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Share to Acute Myeloid Leukemia Research
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Identifiers

PMID: 24806185
DOI: 10.1056/nejmc1316382

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

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Resistance to Arsenic Therapy in Acute Promyelocytic LeukemiaPMID 24806185Read ↗

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Arsenic trioxide resistance in acute promyelocytic leukemia: More to it than PML mutationsSemantic proximity Read ↗

Missense mutations in PML-RARA are critical for the lack of responsiveness to arsenic trioxide treatmentSemantic proximity Read ↗

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