Article
Comparison of newly diagnosed and relapsed patients with acute promyelocytic leukemia treated with arsenic trioxide: insight into mechanisms of resistance.
PloS one - 1 Jan 2015
Chendamarai Ezhilarasi, Ganesan Saravanan, Alex Ansu Abu, Kamath Vandana, Nair Sukesh C, Nellickal Arun Jose, Janet Nancy Beryl, Srivastava Vivi, Lakshmi Kavitha M, Viswabandya Auro, Abraham Aby, Aiyaz Mohammed, Mullapudi Nandita, Mugasimangalam Raja, Padua Rose Ann, Chomienne Christine, Chandy Mammen, Srivastava Alok, George Biju, Balasubramanian Poonkuzhali, Mathews Vikram
Abstract excerpt
There is limited data on the clinical, cellular and molecular changes in relapsed acute promyeloytic leukemia (RAPL) in comparison with newly diagnosed cases (NAPL). We undertook a prospective study to compare NAPL and RAPL patients treated with arsenic trioxide (ATO) based regimens. 98 NAPL and...
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