Article
Carriage of CARD15 variants and smoking as risk factors for resective surgery in patients with Crohn's ileal disease.
Alimentary pharmacology & therapeutics - 15 Sept 2005
Laghi L, Costa S, Saibeni S, Bianchi P, Omodei P, Carrara A, Spina L, Contessini Avesani E, Vecchi M, De Franchis R, Malesci A
Abstract excerpt
BACKGROUND: It is controversial whether CARD15 variants are truly associated with a more severe form of Crohn's disease. The relative role of CARD15 genotype and smoking in Crohn's disease progression is also debated. AIM: To investigate the association between CARD15 variants and history of resective surgery in patients with Crohn's ileal disease, taking into account smoking as a possible confounding factor....
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