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The local environment and germline genetic variation predict cancer risk in the UK Biobank prospective cohort.

Environmental research - 15 Jan 2024

Felici Alessio, Peduzzi Giulia, Giorgolo Francesca, Spinelli Andrea, Calderisi Marco, Monreale Anna, Farinella Riccardo, Pellungrini Roberto, Canzian Federico, Campa Daniele

Abstract excerpt

BACKGROUND: There is a growing body of evidence on the effect of the local environment exposure on cancer susceptibility. Nonetheless, several of the associations remain controversial. Moreover, our understanding of the possible interaction between the local environment and the genetic variability is still very limited. OBJECTIVE: The aim of this study was to clarify the role of the local environment and its...

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PMID: 37944693
DOI: 10.1016/j.envres.2023.117562

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