Article
An endogenous, systemic RNAi pathway in plants.
The EMBO journal - 19 May 2010
Dunoyer Patrice, Brosnan Christopher A, Schott Gregory, Wang Yu, Jay Florence, Alioua Abdelmalek, Himber Christophe, Voinnet Olivier
Abstract excerpt
Recent work on metazoans has uncovered the existence of an endogenous RNA-silencing pathway that functionally recapitulates the effects of experimental RNA interference (RNAi) used for gene knockdown in organisms such as Caenorhabditis elegans and Drosophila. The endogenous short interfering (si)RNA involved in this pathway are processed by Dicer-like nucleases from genomic loci re-arranged to form extended...
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