Article
Dissecting Arabidopsis thaliana DICER function in small RNA processing, gene silencing and DNA methylation patterning.
Nature genetics - 1 Jun 2006
Henderson Ian R, Zhang Xiaoyu, Lu Cheng, Johnson Lianna, Meyers Blake C, Green Pamela J, Jacobsen Steven E
Abstract excerpt
Small RNAs have several important biological functions. MicroRNAs (miRNAs) and trans-acting small interfering RNAs (tasiRNAs) regulate mRNA stability and translation, and siRNAs cause post-transcriptional gene silencing of transposons, viruses and transgenes and are important in both the establishment and maintenance of cytosine DNA methylation. Here, we study the role of the four Arabidopsis thaliana DICER-LIKE...
Topics
- DNA Methylation
- Gene Silencing
- Mutation
- RNA Processing, Post-Transcriptional
- RNA, Small Interfering
- Ribonuclease III