Article
Reinforcement of silencing at transposons and highly repeated sequences requires the concerted action of two distinct RNA polymerases IV in Arabidopsis.
Genes & development - 1 Sept 2005
Pontier Dominique, Yahubyan Galina, Vega Danielle, Bulski Agnès, Saez-Vasquez Julio, Hakimi Mohamed-Ali, Lerbs-Mache Silva, Colot Vincent, Lagrange Thierry
Abstract excerpt
Recent genetic and biochemical studies have revealed the existence in plants of a fourth RNA polymerase, RNAPIV, which mediates siRNA accumulation and DNA methylation-dependent silencing of endogenous repeated sequences. Here, we show that Arabidopsis expresses, in fact, two evolutionarily related forms of RNAPIV, hereafter referred to as RNAPIVa and RNAPIVb. These two forms contain the same second-largest...
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