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Infection with multiple hepatitis C virus genotypes detected using commercial tests should be confirmed using next generation sequencing

25 Jun 2019

Abstract excerpt

Current HCV genotyping methods may have some limitations in detecting mixed infections. We aimed to determine the accuracy of genotyping and the detection of mixed-genotype infections using the Abbott-RealTime HCV Genotype II assay (Abbott-RT-PCR) in comparison with a Roche-Next Generation Sequencing assay (Roche-NGS). Plasma samples collected from 139 HCV-infected patients tested with Abbott-RT-PCR, 114 with...

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PMID: 31239457
DOI: 10.1038/s41598-019-42605-z

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