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Article

NFE2L2 polymorphisms, mortality, and metabolism in the general population.

Physiological genomics - 15 Jun 2014

Figarska Sylwia M, Vonk Judith M, Boezen H Marike

Abstract excerpt

The nuclear factor (erythroid-derived 2)-like 2 (NFE2L2 or NRF2) gene regulates transcription of enzymes involved in cellular detoxification and lipids homeostasis. NFE2L2 is associated with pathophysiology of atherosclerosis and chronic obstructive pulmonary disease (COPD). Therefore we studied the relation between NFE2L2 and all-cause, cardiovascular, and COPD mortality and its associations with triglyceride...

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Identifiers

PMID: 24790085
DOI: 10.1152/physiolgenomics.00178.2013
PMCID: PMC4060038

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