Article
A role of Rab29 in the integrity of the trans-Golgi network and retrograde trafficking of mannose-6-phosphate receptor.
PloS one - 1 Jan 2014
Wang Shicong, Ma Zexu, Xu Xiaohui, Wang Zhen, Sun Lixiang, Zhou Yunhe, Lin Xiaosi, Hong Wanjin, Wang Tuanlao
Abstract excerpt
Rab29 (also referred as Rab7L1) is a novel Rab protein, and is recently demonstrated to regulate phagocytosis and traffic from the Golgi to the lysosome. However, its roles in membrane trafficking have not been investigated extensively. Our results in this study revealed that Rab29 is associated with the trans-Golgi network (TGN), and is essential for maintaining the integrity of the TGN, because inhibition of...
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