Article
High- and low-throughput scoring of fat mass and body fat distribution in C. elegans.
Methods (San Diego, Calif.) - 1 Aug 2014
Wählby Carolina, Conery Annie Lee, Bray Mark-Anthony, Kamentsky Lee, Larkins-Ford Jonah, Sokolnicki Katherine L, Veneskey Matthew, Michaels Kerry, Carpenter Anne E, O'Rourke Eyleen J
Abstract excerpt
Fat accumulation is a complex phenotype affected by factors such as neuroendocrine signaling, feeding, activity, and reproductive output. Accordingly, the most informative screens for genes and compounds affecting fat accumulation would be those carried out in whole living animals. Caenorhabditis elegans is a well-established and effective model organism, especially for biological processes that involve organ...
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