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Article

Exploring the association of succinate dehydrogenase complex mutations with lymphoid malignancies.

Familial cancer - 1 Sept 2014

Renella R, Carnevale J, Schneider K A, Hornick J L, Rana H Q, Janeway K A

Abstract excerpt

The succinate dehydrogenase (SDH) complex exerts a fundamental role in mitochondrial cellular respiration and mutations in its encoding genes (SDHA, SDHB, SDHC, SDHD, collectively referred to as SDHx) lead to a number of inherited endocrine cancer predisposition syndromes, including familial paraganglioma/pheochromocytoma. Recent studies suggest a possible role for the SDH complex and other mitochondrial enzymes...

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Source

Identifiers

PMID: 24781345
DOI: 10.1007/s10689-014-9725-4

Genes

SDHB
SDHA
SDHC
SDHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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