Article
Lack of association between TLR4 genetic polymorphisms and diabetic nephropathy in a Chinese population.
BioMed research international - 1 Jan 2014
Peng Danfeng, Wang Jie, Pan Jiemin, Zhang Rong, Tang Shanshan, Jiang Feng, Chen Miao, Yan Jing, Sun Xue, Wang Tao, Wang Shiyun, Bao Yuqian, Jia Weiping
Abstract excerpt
OBJECTIVE: Toll-like receptor 4 (TLR4) plays a central role in innate immunity. Activation of innate immune response and subsequent chronic low-grade inflammation are thought to be involved in the pathogenesis of diabetic nephropathy. In this study, we aimed to investigate whether TLR4 variants a...
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