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Article

Toll-like receptor 4 polymorphisms and their haplotypes modulate the risk of developing diabetic retinopathy in type 2 diabetes patients.

Molecular vision - 1 Jan 2014

Singh Kanhaiya, Kant Shri, Singh Vivek Kumar, Agrawal Neeraj K, Gupta Sanjeev K, Singh Kiran

Abstract excerpt

PURPOSE: Persistent inflammation and impaired neovascularization in type 2 diabetes mellitus (T2DM) patients may lead to development of macro- and microvascular complications. Diabetic retinopathy (DR) is one of the secondary microvascular complications of T2DM. Improper activation of the innate immune system may be an important contributor in the pathophysiology of DR. Toll-like receptor 4 (TLR4) is an important...

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Share to Demography
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetic Retinopathy

Share to Genotyping Techniques

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Share to Polymorphism, Restriction Fragment Length

Share to Toll-Like Receptor 4

Source

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Identifiers

PMID: 24883015
PMCID: PMC4037533

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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