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Article

Age-related changes of protein SUMOylation balance in the AÎ²PP Tg2576 mouse model of Alzheimer's disease

7 Apr 2014

Abstract excerpt

Alzheimer's disease (AD) is a complex disorder that affects the central nervous system causing a severe neurodegeneration. This pathology affects an increasing number of people worldwide due to the overall aging of the human population. In recent years SUMO protein modification has emerged as a possible cellular mechanism involved in AD. Some of the proteins engaged in the physiopathological process of AD, like...

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PMID: 24778618
DOI: 10.3389/fphar.2014.00063

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