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Article

Adenosine A(2A) receptor up-regulates retinal wave frequency via starburst amacrine cells in the developing rat retina.

PloS one - 1 Jan 2014

Huang Pin-Chien, Hsiao Yu-Tien, Kao Shao-Yen, Chen Ching-Feng, Chen Yu-Chieh, Chiang Chung-Wei, Lee Chien-Fei, Lu Juu-Chin, Chern Yijuang, Wang Chih-Tien

Abstract excerpt

BACKGROUND: Developing retinas display retinal waves, the patterned spontaneous activity essential for circuit refinement. During the first postnatal week in rodents, retinal waves are mediated by synaptic transmission between starburst amacrine cells (SACs) and retinal ganglion cells (RGCs). The neuromodulator adenosine is essential for the generation of retinal waves. However, the cellular basis underlying...

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Identifiers

PMID: 24777042
DOI: 10.1371/journal.pone.0095090
PMCID: PMC4002430

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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