Article
Retinal waves in mice lacking the beta2 subunit of the nicotinic acetylcholine receptor.
Proceedings of the National Academy of Sciences of the United States of America - 9 Sept 2008
Sun Chao, Warland David K, Ballesteros Jose M, van der List Deborah, Chalupa Leo M
Abstract excerpt
The structural and functional properties of the visual system are disrupted in mutant animals lacking the beta2 subunit of the nicotinic acetylcholine receptor. In particular, eye-specific retinogeniculate projections do not develop normally in these mutants. It is widely thought that the developing retinas of beta2(-/-) mutants do not manifest correlated activity, leading to the notion that retinal waves play an...
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