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Article

Lineage-dependent skewing of loss of heterozygosity (LOH) of KRAS gene in a case of juvenile myelomonocytic leukemia.

European journal of haematology - 1 Feb 2015

Tokuda Kiriko, Eguchi-Ishimae Minenori, Iwabuki Hidehiko, Kawakami Sanae, Tauchi Hisamichi, Ishii Eiichi, Eguchi Mariko

Abstract excerpt

Juvenile myelomonocytic leukemia (JMML) is a clonal disease arising from abnormal hematopoietic stem cells, although the involvement of lymphoid lineage differs among reported cases. Here, we present a case of JMML with a KRAS G13D mutation. The mutation was detected in various hematopoietic line...

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Source

Identifiers

PMID: 24766281
DOI: 10.1111/ejh.12355

Genes

KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24766281-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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