Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RAS Pathway Mutation Patterns in Patients With Juvenile Myelomonocytic Leukemia: A Developing Country Single-center Experience.

Clinical lymphoma, myeloma & leukemia - 1 Jul 2020

Hamdy Nayera, Bokhary Hossam, Elsayed Amr, Hozayn Walaa, Soliman Sonya, Salem Sherine, Alsheshtawi Khaled, Abdalla Amr, Hafez Hanafy, Hammad Mahmoud

Abstract excerpt

INTRODUCTION: Juvenile myelomonocytic leukemia (JMML) is a rare clonal myelodysplastic/myeloproliferative neoplasm of early childhood. Historically, it was difficult to diagnose clinically, as patients present with manifestations shared with other hematologic malignancies or viral infections. It is now clear that JMML is a disease of hyperactive RAS signaling. PATIENTS AND METHODS: We examined the bone marrow of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child, Preschool
Share to Developing Countries

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, ras

Share to Infant

Share to Leukemia, Myelomonocytic, Juvenile

Share to Mutation

Share to Signal Transduction

Source

Identifiers

PMID: 32209330
DOI: 10.1016/j.clml.2020.02.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RAS Pathway Mutation Patterns in Patients With Juvenile Myelomonocytic Leukemia: A Developing Country Single-center Experience.PMID 32209330Read ↗

Characteristics of RAS pathway mutations in juvenile myelomonocytic leukaemia: a single-institution study from Korea.Semantic proximity Read ↗

Gene mutations in the Ras pathway and the prognostic implication in Korean patients with juvenile myelomonocytic leukemia.Semantic proximity Read ↗

Childhood Myelodysplastic Syndrome: Focus on the Approach to Diagnosis and Treatment of Juvenile Myelomonocytic LeukemiaSemantic proximity Read ↗

Juvenile myelomonocytic leukemia - A bona fide RASopathy syndrome.Semantic proximity Read ↗

Morphologic and Immunophenotypic Differences in Juvenile Myelomonocytic Leukemias With CBL and Other Canonical RAS-pathway Gene Mutations: A Single Institutional Experience.Semantic proximity Read ↗

Juvenile myelomonocytic leukemia: who’s the driver at the wheel?Semantic proximity Read ↗

Recent advances in the pathogenesis and management of juvenile myelomonocytic leukaemia.Semantic proximity Read ↗

Juvenile myelomonocytic leukemia: epidemiology, etiopathogenesis, diagnosis, and management considerations.Semantic proximity Read ↗

Juvenile myelomonocytic leukemia.Semantic proximity Read ↗

[Juvenile myelomonocytic leukemia (JMML): recent advances in molecular pathogenesis and treatment].Semantic proximity Read ↗

Targeted therapy in juvenile myelomonocytic leukemia: Where are we now?Semantic proximity Read ↗

Bedside to bench in juvenile myelomonocytic leukemia: insights into leukemogenesis from a rare pediatric leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.