Article
Characteristics of RAS pathway mutations in juvenile myelomonocytic leukaemia: a single-institution study from Korea.
British journal of haematology - 1 Dec 2021
Kim Hoon Seok, Lee Jae Wook, Kang Dain, Yu Haein, Kim Yeojae, Kang Hyunhye, Lee Jong-Mi, Ahn Ari, Cho Bin, Kim Seongkoo, Chung Nack-Gyun, Kim Yonggoo, Kim Myungshin
Abstract excerpt
Juvenile myelomonocytic leukaemia (JMML), a rare clonal haematopoietic disorder of childhood, is characterised as a myelodysplastic/myeloproliferative neoplasm. Despite ground-breaking genetic discoveries, JMML remains difficult to diagnose given its diverse clinical features and disease course. A total of 24 patients with JMML were diagnosed and treated at a single institution, and their genetic profiles and...
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