Article
Genetic risk assessment for cardiovascular disease with seven genes associated with plasma C-reactive protein concentrations in Asian populations.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jul 2014
Hong Eun Pyo, Kim Dong Hyun, Suh Jun Gyo, Park Ji Wan
Abstract excerpt
Plasma C-reactive protein (CRP) level is a predictor of cardiovascular risk. We performed a meta-analysis on the effect of 12 single-nucleotide polymorphisms (SNPs) within 8 candidate loci in 36 752 Asians. In addition, we created weighted genetic risk scores (wGRSs) to evaluate the combined effects of genetic variants, which were suggested in the meta-analysis, for predicting the risks of elevated CRP levels as...
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