Article
A MAP3k1 SNP predicts survival of gastric cancer in a Chinese population.
PloS one - 1 Jan 2014
Wei Xiaowei, Zhang Enke, Wang Chun, Gu Dongying, Shen Lili, Wang Meilin, Xu Zhi, Gong Weida, Tang Cuiju, Gao Jinglong, Chen Jinfei, Zhang Zhengdong
Abstract excerpt
OBJECTIVES: Genome-wide association studies (GWAS) have demonstrated that the single nucleotide polymorphism (SNP) MAP3K1 rs889312 is a genetic susceptibility marker significantly associated with a risk of hormone-related tumors such as breast cancer. Considering steroid hormone-mediated signaling pathways have an important role in the progression of gastric cancer, we hypothesized that MAP3K1 rs889312 may be...
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