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Article

Somatic mutation in acute myelogenous leukemia cells imitate novel germline HLA-A allele: a case report.

Tissue antigens - 1 Jun 2014

Mrazek F, Onderkova J, Szotkowski T, Königova N, Ambruzova Z, Raida L

Abstract excerpt

A somatic mutation of the human leukocyte antigen (HLA)-A gene revealed in tumour cells of acute myelogenous leukemia (AML) is described. A patient with AML and her siblings were routinely typed for HLA in order to find a suitable donor for haematopoietic stem cell transplantation. Sequencing-based typing of the initial patient's sample characterized by high proportion of blasts revealed unknown G/A exchange at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24758284
DOI: 10.1111/tan.12362

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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