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Article

Loss or down-regulation of HLA class I expression at the allelic level in freshly isolated leukemic blasts.

Cancer science - 1 Jan 2007

Masuda Kozo, Hiraki Akio, Fujii Nobuharu, Watanabe Toshiyuki, Tanaka Motoyuki, Matsue Kosei, Ogama Yoichiro, Ouchida Mamoru, Shimizu Kenji, Ikeda Kazuma, Tanimoto Mitsune

Abstract excerpt

Loss or down-regulation of human leukocyte antigen (HLA) class I expression has been demonstrated in a variety of solid tumors. To date, such altered HLA expression has not been studied extensively in freshly isolated leukemic blasts. If it occurs, leukemic cells could escape T-cell surveillance...

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Source

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Identifiers

PMID: 17083564
DOI: 10.1111/j.1349-7006.2006.00356.x
PMCID: PMC11158761

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17083564-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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