Article
Conversion of female germline stem cells from neonatal and prepubertal mice into pluripotent stem cells.
Journal of molecular cell biology - 1 Apr 2014
Wang Hu, Jiang Manxi, Bi Haiwei, Chen Xuejin, He Lin, Li Xiaoyong, Wu Ji
Abstract excerpt
Pluripotent stem cells derived from neonatal or adult testes are a useful tool to examine the mechanisms of pluripotency and a resource for cell-based therapies. However, therapies using these cells will only benefit males but not females. Recently, female germline stem cells (FGSCs) were discovered in ovaries. Whether FGSCs can be converted into pluripotent stem cells, similar to spermatogonial stem cells, is...
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