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Making gametes from pluripotent stem cells – a promising role for very small embryonic-like stem cells

1 Jan 2014

Abstract excerpt

The urge to have one's own biological child supersedes any desire in life. Several options have been used to obtain gametes including pluripotent stem cells (embryonic ES and induced pluripotent iPS stem cells); gonadal stem cells (spermatogonial SSCs, ovarian OSCs stem cells), bone marrow, mesenchymal cells and fetal skin. However, the field poses a huge challenge including inefficient existing protocols for...

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PMID: 25421462
DOI: 10.1186/1477-7827-12-114

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