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Article

A novel genetic score approach using instruments to investigate interactions between pathways and environment: application to air pollution.

PloS one - 1 Jan 2014

Bind Marie-Abele, Coull Brent, Suh Helen, Wright Robert, Baccarelli Andrea, Vokonas Pantel, Schwartz Joel

Abstract excerpt

Air pollution has been associated with increased systemic inflammation markers. We developed a new pathway analysis approach to investigate whether gene variants within relevant pathways (oxidative stress, endothelial function, and metal processing) modified the association between particulate air pollution and fibrinogen, C-reactive protein (CRP), intercellular adhesion molecule-1 (ICAM-1), and vascular cell...

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Identifiers

PMID: 24755831
DOI: 10.1371/journal.pone.0096000
PMCID: PMC3995963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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