NQO1 gene rs1800566 variant is not associated with risk for multiple sclerosis.

doi:10.1186/1471-2377-14-87

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Article

NQO1 gene rs1800566 variant is not associated with risk for multiple sclerosis.

BMC neurology - 23 Apr 2014

Agúndez José A G, García-Martín Elena, Martínez Carmen, Benito-León Julián, Millán-Pascual Jorge, Calleja Patricia, Díaz-Sánchez María, Pisa Diana, Turpín-Fenoll Laura, Alonso-Navarro Hortensia, Ayuso-Peralta Lucía, Torrecillas Dolores, Plaza-Nieto José Francisco, Jiménez-Jiménez Félix Javier

Abstract excerpt

BACKGROUND: A possible role of oxidative stress in the pathogenesis of multiple sclerosis (MS) and in experimental autoimmune encephalomyelitis has been suggested. The detoxification enzyme NAD(P)H dehydrogenase, quinone 1 (NQO1) has been found up-regulated in MS lesions. A previous report described an association between the SNP rs1800566 in the NQO1 gene and the risk for MS in the Greek population. The aim of...

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PMID: 24755231
DOI: 10.1186/1471-2377-14-87
PMCID: PMC4022329

Genes

NQO1

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