Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cellular communication via microparticles: role in transfer of multidrug resistance in cancer.

Future oncology (London, England) - 1 Mar 2014

Jaiswal Ritu, Raymond Grau Georges Emile, Bebawy Mary

Abstract excerpt

Multidrug resistance (MDR) continues to be a major impediment to the successful treatment of cancer. The two efflux transporters, P-glycoprotein (P-gp) and MRP1 are major contributors to cancer MDR clinically. The upregulation of P-gp leading to MDR was initially understood to occur via pre- and post-transcriptional mechanisms only. However, we demonstrated that microparticles mediate the intercellular exchange...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Communication

Share to Cell-Derived Microparticles

Share to Drug Resistance, Multiple

Share to Drug Resistance, Neoplasm

Share to Multidrug Resistance-Associated Proteins

Share to Protein Transport

Source

Identifiers

PMID: 24754595
DOI: 10.2217/fon.13.230

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cellular communication via microparticles: role in transfer of multidrug resistance in cancer.PMID 24754595Read ↗

Microparticle-associated nucleic acids mediate trait dominance in cancer.Semantic proximity Read ↗

Microparticles and their emerging role in cancer multidrug resistanceSemantic proximity Read ↗

Microparticles induce multifactorial resistance through oncogenic pathways independently of cancer cell typeSemantic proximity Read ↗

MRP1 and its role in anticancer drug resistanceSemantic proximity Read ↗

Microparticle drug sequestration provides a parallel pathway in the acquisition of cancer drug resistance.Semantic proximity Read ↗

Circulating biosignatures in multiple myeloma and their role in multidrug resistanceSemantic proximity Read ↗

Proteome analysis of multidrug‐resistant, breast cancer–derived microparticlesSemantic proximity Read ↗

Progress in the studies on the molecular mechanisms associated with multidrug resistance in cancersSemantic proximity Read ↗

The network of P-glycoprotein and microRNAs interactionsSemantic proximity Read ↗

Exosomes play an important role in the process of psoralen reverse multidrug resistance of breast cancerSemantic proximity Read ↗

Proteins regulating the intercellular transfer and function of P-glycoprotein in multidrug-resistant cancerSemantic proximity Read ↗

Platelet-derived microparticles provoke chronic lymphocytic leukemia malignancy through metabolic reprogrammingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.