Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microparticles induce multifactorial resistance through oncogenic pathways independently of cancer cell type

2 Dec 2014

Abstract excerpt

Multidrug resistance (MDR) is considered a multifactorial event that favors cancer cells becoming resistant to several chemotherapeutic agents. Numerous mechanisms contribute to MDR, such as P-glycoprotein (Pgp/ABCB1) activity that promotes drug efflux, overexpression of inhibitors of apoptosis proteins (IAP) that contribute to evasion of apoptosis, and oncogenic pathway activation that favors cancer cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to MicroRNA in disease regulation
Share to RNA Interference and Gene Delivery

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25457412
DOI: 10.1111/cas.12566

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microparticles induce multifactorial resistance through oncogenic pathways independently of cancer cell typePMID 25457412Read ↗

Cellular communication via microparticles: role in transfer of multidrug resistance in cancer.Semantic proximity Read ↗

Microparticle-associated nucleic acids mediate trait dominance in cancer.Semantic proximity Read ↗

Microparticles and their emerging role in cancer multidrug resistanceSemantic proximity Read ↗

Progress in the studies on the molecular mechanisms associated with multidrug resistance in cancersSemantic proximity Read ↗

Expression of Chemoresistance-Associated ABC Proteins in Hepatobiliary, Pancreatic and Gastrointestinal CancersSemantic proximity Read ↗

Proteome analysis of multidrug‐resistant, breast cancer–derived microparticlesSemantic proximity Read ↗

Multidrug Resistance: Are We Still Afraid of the Big Bad WolfSemantic proximity Read ↗

Circulating biosignatures in multiple myeloma and their role in multidrug resistanceSemantic proximity Read ↗

Exosomes play an important role in the process of psoralen reverse multidrug resistance of breast cancerSemantic proximity Read ↗

Managing Cancer Drug Resistance from the Perspective of InflammationSemantic proximity Read ↗

Microparticle drug sequestration provides a parallel pathway in the acquisition of cancer drug resistance.Semantic proximity Read ↗

New mechanisms of multidrug resistance: an introduction to the Cancer Drug Resistance special collectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.