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Circulating biosignatures in multiple myeloma and their role in multidrug resistance

29 Apr 2023

Abstract excerpt

A major obstacle to chemotherapeutic success in cancer treatment is the development of drug resistance. This occurs when a tumour fails to reduce in size after treatment or when there is clinical relapse after an initial positive response to treatment. A unique and serious type of resistance is multidrug resistance (MDR). MDR causes the simultaneous cross resistance to unrelated drugs used in chemotherapy. MDR...

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PMID: 37120508
DOI: 10.1186/s12943-022-01683-w

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