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Article

Proteome analysis of multidrug‐resistant, breast cancer–derived microparticles

1 Jan 2014

Abstract excerpt

Cancer multidrug resistance (MDR) occurs when cancer cells evade the cytotoxic actions of chemotherapeutics through the active efflux of drugs from within the cells. Our group have previously demonstrated that multidrug-resistant breast cancer cells spontaneously shed microparticles (MPs) and that these MPs can transfer resistance to drug-responsive cells and confer MDR on those cells in as little as 4 h....

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PMID: 25206959
DOI: 10.3402/jev.v3.24384

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