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Article

Family-based clinical associations and functional characterization of the serotonin 2A receptor gene (HTR2A) in autism spectrum disorder.

Autism research : official journal of the International Society for Autism Research - 1 Aug 2014

Smith Ryan M, Banks Wesley, Hansen Emily, Sadee Wolfgang, Herman Gail E

Abstract excerpt

The serotonin 2A receptor gene (HTR2A) harbors two functional single nucleotide polymorphisms (SNPs) that are frequent in populations of African and European descent; rs6311, which affects mRNA expression, and rs6314, which changes the amino acid sequence of the encoded protein and affects the signaling properties of the receptor. Multiple clinical associations support a role for these SNPs in cognitive and...

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PMID: 24753316
DOI: 10.1002/aur.1383
PMCID: PMC4134733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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