Article
Allelic variants in HTR3C show association with autism.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2009
Rehnström Karola, Ylisaukko-oja Tero, Nummela Ilona, Ellonen Pekka, Kempas Elli, Vanhala Raija, von Wendt Lennart, Järvelä Irma, Peltonen Leena
Abstract excerpt
Autism spectrum disorders (ASDs) are severe neurodevelopmental disorders with a strong genetic component. Only a few predisposing genes have been identified so far. We have previously performed a genome-wide linkage screen for ASDs in Finnish families where the most significant linkage peak was identified at 3q25-27. Here, 11 positional and functionally relevant candidate genes at 3q25-27 were tested for...
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