Article
Activation of the aryl hydrocarbon receptor affects activation and function of human monocyte-derived dendritic cells.
Clinical and experimental immunology - 1 Aug 2014
Wang C, Ye Z, Kijlstra A, Zhou Y, Yang P
Abstract excerpt
Aryl hydrocarbon receptor (AhR) is well known for mediating the toxic effects of dioxin-containing pollutants, but has also been shown to be involved in the natural regulation of the immune response. In this study, we investigated the effect of AhR activation by its endogenous ligands 6-formylindolo[3,2-b]carbazole (FICZ) and 2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE) on the...
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