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Article

A high percentage of BRAFV600E alleles in papillary thyroid carcinoma predicts a poorer outcome.

The Journal of clinical endocrinology and metabolism - 1 Jul 2012

Guerra Anna, Fugazzola Laura, Marotta Vincenzo, Cirillo Massimo, Rossi Stefania, Cirello Valentina, Forno Irene, Moccia Tania, Budillon Alfredo, Vitale Mario

Abstract excerpt

CONTEXT: BRAF(V600E) is considered a negative prognostic marker in papillary thyroid carcinoma (PTC), but unexplained conflicting results are present in the literature. In light of the new finding that most PTC consist of a mixture of tumor cells with wild-type and mutant BRAF, we examined the associations between the percentage of BRAF(V600E) alleles and both the clinicopathological parameters at time of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 22508706
DOI: 10.1210/jc.2011-3106

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

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A high percentage of BRAFV600E alleles in papillary thyroid carcinoma predicts a poorer outcome.PMID 22508706Read ↗

Clinical implications of the extent of BRAFV600E alleles in patients with papillary thyroid carcinoma.Semantic proximity Read ↗

Significance of allelic percentage of BRAF c.1799T > A (V600E) mutation in papillary thyroid carcinoma.Semantic proximity Read ↗

Quantification of BRAF V600E alleles predicts papillary thyroid cancer progression.Semantic proximity Read ↗

Allele percentage of the BRAF V600E mutation in papillary thyroid carcinomas and corresponding lymph node metastases: no evidence for a role in tumor progression.Semantic proximity Read ↗

Association of BRAFV600E mutation with clinicopathological features of papillary thyroid carcinoma: a study on a Chinese population.Semantic proximity Read ↗

The ratio of BRAFV600E alleles can be used to assess the biological behavior of papillary thyroid carcinomaSemantic proximity Read ↗

Association of BRAF V600E Allele Frequency With Clinicopathologic Outcomes in Papillary Thyroid CancerSemantic proximity Read ↗

BRAF<sup>V600E</sup> Mutation is Associated with Tumor Aggressiveness in Papillary Thyroid CancerSemantic proximity Read ↗

BRAF(V600E) Mutation is Associated with Decreased Disease-Free Survival in Papillary Thyroid Cancer.Semantic proximity Read ↗

Prevalence and Clinicopathological Significance of BRAF V600E Mutation in Papillary Thyroid Carcinoma: A Retrospective Cohort Study from Kerala, IndiaSemantic proximity Read ↗

The Primary Occurrence of<i>BRAF<sup>V600E</sup></i>Is a Rare Clonal Event in Papillary Thyroid CarcinomaSemantic proximity Read ↗

BRAF V600E Mutation Lacks Association with Poorer Clinical Prognosis in Papillary Thyroid Carcinoma.Semantic proximity Read ↗

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