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Article

Nonmyocytic androgen receptor regulates the sexually dimorphic development of the embryonic bulbocavernosus muscle.

Endocrinology - 1 Jul 2014

Ipulan Lerrie Ann, Suzuki Kentaro, Sakamoto Yuki, Murashima Aki, Imai Yuuki, Omori Akiko, Nakagata Naomi, Nishinakamura Ryuichi, Valasek Petr, Yamada Gen

Abstract excerpt

The bulbocavernosus (BC) is a sexually dimorphic muscle observed only in males. Androgen receptor knockout mouse studies show the loss of BC formation. This suggests that androgen signaling plays a vital role in its development. Androgen has been known to induce muscle hypertrophy through satellite cell activation and myonuclei accretion during muscle regeneration and growth. Whether the same mechanism is present...

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Share to Cyclin-Dependent Kinase Inhibitor p21
Share to Embryo, Mammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred ICR

Share to Microscopy, Electron, Scanning

Share to Muscle Development

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Share to Receptors, Androgen

Source

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Identifiers

PMID: 24742196
DOI: 10.1210/en.2014-1008
PMCID: PMC4060183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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