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Article

Sertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testis

6 May 2014

Abstract excerpt

Sertoli cells (SCs) regulate testicular fate in the differentiating gonad and are the main regulators of spermatogenesis in the adult testis; however, their role during the intervening period of testis development, in particular during adult Leydig cell (ALC) differentiation and function, remains largely unknown. To examine SC function during fetal and prepubertal development we generated two transgenic mouse...

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PMID: 24803659
DOI: 10.1242/dev.107029

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