Article

Androgen receptor determines skeletal muscle sexual dimorphism

2026-08-18

Abstract excerpt

The molecular and functional bases of sexual dimorphism in skeletal muscle remain poorly understood. The androgen receptor (AR) is a major regulator of sex-biased gene expression in muscle, but its genomic targets and associated coregulators in vivo are incompletely defined. Using ChIL-seq and an AirID-AR knock-in mouse, we mapped AR-bound genes and AR-associated proteins in skeletal muscle and identified histone...

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Literature Corpus work: 52b5dc3d-f7ef-50d4-b4a3-b1bae612107e
DOI: 10.64898/2026.08.17.745371

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