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HPV-related Oropharyngeal Squamous Cell Carcinoma: p16INK4A Immunohistochemistry or HPV Genotyping?

Anticancer research - 1 Sept 2015

Orsaria Maria, Marzinotto Stefania, De Marchi Luca, Giacomarra Vittorio, Boria Silvio, Rubini Corrado, Londero Ambrogio Pietro, Di Loreto Carla, Mariuzzi Laura

Abstract excerpt

BACKGROUND: Infection with high-risk human papillomavirus (HPV) is linked to a sub-group of squamous cell oropharyngeal tumors (OPSCC). Our aim was to compare an HPV Polymerase Chain Reaction (PCR) assay and p16(INK4A) expression status by immunohistochemistry (IHC) as a surrogate marker. MATERIALS AND METHODS: This was a retrospective study considering patients affected by squamous cell oropharyngeal tumors. All...

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PMID: 26254363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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