Article
Exciting cell membranes with a blustering heat shock.
Biophysical journal - 15 Apr 2014
Liu Qiang, Frerck Micah J, Holman Holly A, Jorgensen Erik M, Rabbitt Richard D
Abstract excerpt
Brief heat shocks delivered to cells by pulsed laser light can evoke action potentials in neurons and contraction in cardiomyocytes, but the primary biophysical mechanism has been elusive. In this report we show in the neuromuscular junction of Caenorhabditis elegans that application of a 500°C/s heat shock for 500 μs evoked ~35 pA of excitatory current and injected ~23 fC(femtocoulomb) of charge into the cell...
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