Article

Optical modulation of excitation-contraction coupling in human induced pluripotent stem cell-derived cardiomyocytes

2022-09-23

Abstract excerpt

Non-genetic photostimulation is a novel and rapidly growing multidisciplinary field of research that aims to induce light sensitivity in living systems by exploiting exogeneous phototransducers. Here we propose a recently synthetized intramembrane photoswitch, based on an azobenzene derivative (Ziapin2), for optical pacing of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The light-mediate...

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Literature Corpus work: 9e2bcf10-e4a1-5263-8c15-94cdeb079d08
DOI: 10.1101/2022.09.22.508828

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