Article
Temporal dynamics of neuronal activation by Channelrhodopsin-2 and TRPA1 determine behavioral output in Drosophila larvae.
Journal of neurophysiology - 1 Jun 2009
Pulver Stefan R, Pashkovski Stanislav L, Hornstein Nicholas J, Garrity Paul A, Griffith Leslie C
Abstract excerpt
In recent years, a number of tools have become available for remotely activating neural circuits in Drosophila. Despite widespread and growing use, very little work has been done to characterize exactly how these tools affect activity in identified fly neurons. Using the GAL4-UAS system, we expressed blue light-gated Channelrhodopsin-2 (ChR2) and a mutated form of ChR2 (H134R-ChR2) in motor and sensory neurons of...
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