Article
The voltage sensor module in sodium channels.
Handbook of experimental pharmacology - 1 Jan 2014
Groome James R
Abstract excerpt
The mechanism by which voltage-gated ion channels respond to changes in membrane polarization during action potential signaling in excitable cells has been the subject of research attention since the original description of voltage-dependent sodium and potassium flux in the squid giant axon. The cloning of ion channel genes and the identification of point mutations associated with channelopathy diseases in muscle...
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