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Article

The pro-inflammatory cytokine, interleukin-6, enhances the polarization of alternatively activated macrophages.

PloS one - 1 Jan 2014

Fernando Maria Ruweka, Reyes Jose Luis, Iannuzzi Jordan, Leung Gabriella, McKay Derek Mark

Abstract excerpt

Macrophages are important innate immune cells that are associated with two distinct phenotypes: a pro-inflammatory (or classically activated) subset with prototypic macrophage functions such as inflammatory cytokine production and bactericidal activity, and an anti-inflammatory (or alternatively activated (AAM)) subset linked with wound healing and tissue repair processes. In this study, we examined the effect of...

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Identifiers

PMID: 24736635
DOI: 10.1371/journal.pone.0094188
PMCID: PMC3988054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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