Article
The first trimester gravid serum regulates procalcitonin expression in human macrophages skewing their phenotype in vitro.
Mediators of inflammation - 1 Jan 2014
Rami Damiano, La Bianca Martina, Agostinis Chiara, Zauli Giorgio, Radillo Oriano, Bulla Roberta
Abstract excerpt
Procalcitonin (PCT) is one of the best diagnostic and prognostic markers in clinical practice, widely used to evaluate the evolution of bacterial infections. Although it is mainly produced by thyroid, during sepsis almost all the peripheral tissues are involved in PCT production. Parenchymal cells have been suggested as the main source of PCT expression; however the contribution of macrophages is not clear yet....
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