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Article

Diabetes during pregnancy influences Hofbauer cells, a subtype of placental macrophages, to acquire a pro-inflammatory phenotype.

Biochimica et biophysica acta - 1 Dec 2013

Sisino Giorgia, Bouckenooghe Thomas, Aurientis Sandra, Fontaine Pierre, Storme Laurent, Vambergue Anne

Abstract excerpt

Growing evidence indicates that maternal pathophysiological conditions, such as diabetes, influence fetal growth and could program metabolic disease in adulthood. Placental cells, particularly Hofbauer cells (HBCs), which are placental macrophages characterized by an anti-inflammatory profile (M2), can sense the modified maternal environment. The goal of this study was to investigate the direct effect of...

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Identifiers

PMID: 23872577
DOI: 10.1016/j.bbadis.2013.07.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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