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Article

<scp>H</scp>edgehog pathway as a potential treatment target in human cholangiocarcinoma

15 Apr 2014

Abstract excerpt

BACKGROUND: Innovative treatment concepts targeting essential signaling pathways may offer new chances for patients suffering from cholangiocarcinoma (CCC). For that, we performed a systematic molecular genetic analysis concerning the Hedgehog activity in human CCC samples and analyzed the effect of Hh inhibition on CCC cells in vitro and in vivo. METHODS: Activation of the Hh pathway was analyzed in 50 human CCC...

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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PMID: 24733827
DOI: 10.1002/jhbp.107

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