Article
Role of the Notch signaling in cholangiocarcinoma
22 Mar 2017
Abstract excerpt
INTRODUCTION: Cholangiocarcinoma (CCA) is an emerging cancer entity of the liver, associated with poor outcome and characterized by resistance to conventional chemotherapeutic treatments. In the last decade, many signaling pathways associated with CCA development and progression have been identified and are currently under intense investigation. Cumulating evidence indicates that the Notch cascade, a...
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